PBIO-502-01 Human Physiology (8) A comprehensive course designed to provide the student with a fundamental understanding of the mechanisms of body function. The concepts are presented at various levels of organization, ranging from cellular and molecular to tissue and organ systems. Emphasis is also placed on the integrated regulation among organ systems. Methods of instruction include lectures, small group tutorial sessions, problem solving workshops, case discussion, demonstrations, and clinical correlations. Professor Mulroney and Staff
PBIO-502-02 Human Physiology (5) Similar to 502-01 but limited to lecture, problem solving workshops and clinical correlations. This offering is intended only for those students who have previously taken an undergraduate or graduate course in mammalian physiology. Permission of the instructor is required. Professor Haramati and Staff
PBIO-503-01 Advanced Cardiovascular Physiology (2) This course covers current concepts and recent advances in human cardiovascular physiology with an emphasis on integrated regulation. Professor Myers
PBIO-511-01 Advanced Renal Physiology (2) This course covers current concepts and recent advances in renal physiology with an emphasis on the role of the kidneys in the homeostatic regulation of water and electrolyte balance. Professor Mulroney
PBIO-524 Cell and Membrane Physiology (2) Study of the function of biological membranes and cells.
PBIO-527 Advanced Neuroendocrinology (2) This course deals with the most recent information on neuropeptide hormones and cytokines produced by the central nervous system and their influence on endocrine
systems and behavior. The course is intended for graduate students, but is also open to medical students, fellows and residents. A graduate level course in human physiology and permission of the instructor are prerequisites. Professor Lumpkin
PBIO-534 Cellular and Molecular Physiology (4) This is a lecture course on selected topics in cellular and molecular physiology. Although it is primarily intended for students enrolled in the Masters Program in Physiology, it is open to all graduate students. The emphasis will be on the integration of molecular mechanisms of cellular maintenance and communication to yield a working knowledge of the molecular and biochemical underpinnings of physiology. Professor Sherman
PBIO-535 Integrative Physiology (2) This course covers selected topics in physiology and current concepts regarding the integration of physiological processes at the tissue, organ system, and whole body levels. Professor Hamosh
PBIO-547 Molecular Neurophysiology (2) This course covers recent advances in understanding neuronal cell function with combined single-channel recording and recombinant DNA techniques. Professor Vicini
PBIO-549 Oxygen, Gene Expression, and Cellular Function (2) This course deals with cellular and molecular strategies used by organisms to adapt to changing (low or high) concentrations of O2. Emphasis will
be placed on the regulation of gene expression of the antioxidant enzymes and on the effect of O2 tension and oxygen radicals on cell function with particular emphasis on the lung. Professors Clerch, Massaro
PBIO-550 Platelet-Vascular Cell Biology (2) The objective of the course is to cover recent developments in research in molecular and cell physiology of platelets, vascular smooth muscle and endothelial cells. Professor Myers
PBIO-587,588, 589, 590 Molecular and Cellular Pathophysiology I-IV (2, 2, 2, 2) A year-long course which will provide the student with an understanding of the cellular and genetic mechanisms that underlie organ
system dysfunction. Emphasis will also be placed on comprehension of the interrelationships between failures in several organ systems. The topics are organized into four separate two-credit course blocks (two in the fall and
two in the spring) . Each block will cover a discrete discipline and will require separate registration; students may register for one or more of the course blocks. The methods of instruction will be primarily lectures and small group discussions. The course is intended for graduate students, but is open to medical students, residents and fellows. A graduate level course in human physiology and permission of the instructor are prerequisites.
PBIO-587 Molecular and Cellular Pathophysiology I (2) (Fall)
Professors Hamosh and Jones
PBIO-588 Molecular and Cellular Pathophysiology II (2) (Fall) Professors Haramati and Zukowska
PBIO-589 Molecular and Cellular Pathophysiology III (2) (Spring) Professors Lumpkin and Clarke
PBIO-590 Molecular and Cellular Pathophysiology IV (2) (Spring) Professor Vicini
PBIO-591, 592 Physiology Journal Club (1) Students participate in the weekly discussion of published papers in the scientific literature relevant to various aspects of physiology. Professors Haramati, Myers
PBIO-594 Advanced Muscle Physiology (2) This course deals with the cellular and molecular aspects of regulation of contraction in smooth and striated muscles. An introductory presentation by the instructor in the first session will be followed by a discussion session based on literature handed out after the first session. This course is mainly intended for Ph.D. and M.D. graduate students. A graduate level course in physiology is a prerequisite. Professor
PBIO-595 Tumor Endocrinology (2) This is an advanced course in Tumor Endocrinology with a specific emphasis on the role of hormones in the pathophysiology of diverse cancers. The course will cover the role of
hormones and their receptors in the treatment and diagnosis of cancer. This will include both steroid and polypeptide hormones, and the influence of environmental/nutritional components with endocrine properties. The interactions among endocrine and cytotoxic therapies also will be discussed. Professors Clarke and Wei
PBIO-701, 702 Seminar (1) Presentation of current research data by faculty, senior graduate students, and guests from other scientific institutions. Staff
PBIO-901, 902 Research (3) Professor Lumpkin and staff
PBIO-903, 904 Research (3) Professor Lumpkin and staff
PBIO-905 Physiology Tutorial(Variable)
PBIO-907 Physiology Research (2)
PBIO-908, 909 Tutorial: Research Techniques (2) The objectives of this course are to:
1) teach the student both common and specialized techniques used in physiological research, and
2) introduce students to the research interests of the department faculty. Staff
PBIO-999 Thesis Research--Physiology and Biophysics (1-3) For Ph.D. students only. Professor Lumpkin and Staff
