Growth Regulation of Cancer Program
Overview | Leaders | Research | Publications
Selected Publications
2008
Adhikari S, Manthena PV, Uren A, Roy R. Expression, purification and characterization of codon-optimized human N-methylpurine-DNA glycosylase from Escherichia coli. Protein Expr Purif 2008;58:257-262.
Adhikari S, Uren A, Roy R. Dipole-dipole interaction stabilizes the transition state of apurinic/apyrimidinic endonuclease--abasic site interaction. J Biol Chem 2008;283:1334-1339.
Baek HJ, Lim SC, Kitisin K, Jogunoori W, Tang Y, Marshall MB, Mishra B, Kim TH, Cho KH, Kim SS, Mishra L. Hepatocellular cancer arises from loss of transforming growth factor beta signaling adaptor protein embryonic liver fodrin through abnormal angiogenesis. Hepatology 2008;48:1128-1137.
Bourne C, Lee S, Venkataiah B, Lee A, Korba B, Finn MG, Zlotnick A. Small-molecule effectors of hepatitis B virus capsid assembly give insight into virus lifecycle. J Virol 2008;82:10262-10270.
Bouzahzah B, Yurchenko V, Nagajyothi F, Hulit J, Sadofsky M, Braunstein VL, Mukherjee S, Weiss H, Machado FS, Pestell RG, Lisanti MP, Tanowitz HB, Albanese C. Regulation of host cell cyclin D1 by Trypanosoma cruzi in myoblasts. Cell Cycle 2008;7:500-503.
Byers S, Pishvaian M, Mishra L, Glazer RI. TGF beta, Notch, and Wnt in normal and malignant stem cells: differentiating agents and epigenetic modulation. 2008.
Chau MN, Banerjee PP. Development of a STAT3 reporter prostate cancer cell line for high throughput screening of STAT3 activators and inhibitors. Biochem Biophys Res Commun 2008;377:627-631.
Chen K, Fallen S, Abaan HO, Hayran M, Gonzalez C, Wodajo F, MacDonald T, Toretsky JA, Uren, A. Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival. Pediatr Blood Cancer 2008;51:349-355.
Endo Y, Beauchamp E, Woods D, Taylor WG, Toretsky JA, Uren A, Rubin JS. Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism. Mol Cell Biol 2008;28:2368-2379.
Endo Y, Deonauth K, Prahalad P, Hoxter B, Zhu Y, Byers SW. Role of Sox-9, ER81 and VE-cadherin in retinoic acid-mediated trans-differentiation of breast cancer cells. PLoS ONE 2008;3:e2714
Fereshteh MP, Tilli MT, Kim SE, Xu J, O'Malley BW, Wellstein A, Furth PA, Riegel AT. The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Res 2008;68:3697-3706.
Fishbein T, Novitskiy G, Mishra L, Matsumoto C, Kaufman S, Goyal S, Shetty K, Johnson L, Lu A, Wang A, Hu F, Kallakury B, Lough D, Zasloff, M. NOD2-expressing bone marrow-derived cells appear to regulate epithelial innate immunity of the transplanted human small intestine. Gut 2008;57:323-330.
Foshay KM, Gallicano GI. Regulation of Sox2 by STAT3 initiates commitment to the neural precursor cell fate. Stem Cells Dev 2008;17:269-278.
Frech MS, Torre KM, Robinson GW, Furth PA. Loss of cyclin D1 in concert with deregulated estrogen receptor alpha expression induces DNA damage response activation and interrupts mammary gland morphogenesis. Oncogene 2008;27:3186-3193.
Glasgow E, Mishra L. Transforming growth factor-beta signaling and ubiquitinators in cancer. Endocr Relat Cancer 2008;15:59-72.
He AR, Mendelson J., Blake T, Mishra L, Marshall JL. Stem cells in gastrointestinal cancers. Dis Markers 2008;24:217-222.
He Z, Jiang J, Kokkinaki M, Golestaneh N, Hofmann MC, Dym M. Gdnf upregulates c-Fos transcription via the Ras/Erk1/2 pathway to promote mouse spermatogonial stem cell proliferation. Stem Cells 2008;26:266-278.
Jones LP, Tilli MT, Assefnia S, Torre K, Halama ED, Parrish A, Rosen EM, Furth, PA. Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer. Oncogene 2008;27:794-802.
Kang HJ, Kim HJ, Cho CH, Hu Y, Li R, Bae I. BRCA1 transcriptional activity is enhanced by interactions between its AD1 domain and AhR. Cancer Chemother Pharmacol 2008;62:965-975.
Kang HJ, Kim HJ, Kwon SH, Kang BD, Eling TE, Lee SH, Bae I. BRCA1 modulates sensitivity to 5F-203 by regulating xenobiotic stress-inducible protein levels and EROD activity. Cancer Chemother Pharmacol 2008;62:689-697
Kim DC, Sabarish R, Baek SH, Kwon SH, Kwon KY, Cha SD, Bae I, Cho CH. Induction of Growth Inhibition and Apoptosis in Human Uterine Leiomyoma Cells by Isoliquiritigenin. Reprod Sci. 2008;15(6):552-558.
Korba BE, Montero AB, Farrar K, Gaye K, Mukerjee S, Ayers MS, Rossignol JF. Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication. Antiviral Res 2008;77:56-63.
Korba BE, Elazar M, Liu P, Rossignol JF, Glenn JS. Studies of the potential for nitazoxanide or tizoxanide resistance in hepatitis C virus replication-containing cell lines. Antiviral Agents Chemother 2009; In Press.
Krawczyk E, Suprynowicz FA, Liu X, Dai Y, Hartmann DP, Hanover J, Schlegel R. Koilocytosis: a cooperative interaction between the human papillomavirus E5 and E6 oncoproteins. Am J Pathol 2008;173:682-688.
Krawczyk E, Hanover JA, Schlegel R, Suprynowicz FA. Karyopherin beta3: a new cellular target for the HPV-16 E5 oncoprotein. Biochem Biophys Res Commun 2008;371:684-688.
Kwon S, Ramachandran S, Park JK, Kwon KY, Park JC, Cha SD, Bae I, Cho CH. Loss of cyclin G1 expression in leiomyoma cells induces apoptosis. Reproductive Science 2008;15:400-410.
Laguinge LM, Samara RN, Wang W, El Deiry WS, Corner G, Augenlicht L, Mishra L, Jessup JM. DR5 receptor mediates anoikis in human colorectal carcinoma cell lines. Cancer Res 2008;68:909-917.
Li C, Prichard MN, Korba BE, Drach JC, Zemlicka J. Fluorinated methylenecyclopropane analogues of nucleosides. Synthesis and antiviral activity of (Z)- and (E)-9-{[(2-fluoromethyl-2-hydroxymethyl)-cyclopropylidene]methyl} adenine and -guanine. Bioorg Med Chem 2008;16:2148-2155.
Li F, Li L, Qin X, Pan W, Feng F, Chen F, Zhu B, Liao D, Tanowitz H, Albanese C, Chen L. Apelin-induced vascular smooth muscle cell proliferation: the regulation of cyclin D1. Front Biosci 2008;13:3786-3792.
Liu X, Dakic A, Chen R, Disbrow GL, Dai Y, Zhang Y, Simic V, Schlegel R. Cell-restricted immortalization by HPV correlates with telomerase activation and engagement of the hTERT promoter by Myc. J. Virol. 2008 Dec 82(23):11568-76.
Liu X, Roberts J, Dakic A, Zhang Y, Schlegel R. HPV E7 contributes to the telomerase activity of immortalized and tumorigenic cells and augments E6-induced hTERT promoter function. Virology 2008;375:611-623.
Mishra L. The 21st century hepatologist and a systems biology based approach to liver diseases. Hepatology 2008;48:1731-1733.
Mukherjee S, Nagajyothi F, Mukhopadhyay A, Machado FS, Belbin TJ, Campos de Carvalho, Guan F, Albanese C, Jelicks LA, Lisanti MP, Silva JS, Spray DC, Weiss LM, Tanowitz HB. Alterations in myocardial gene expression associated with experimental Trypanosoma cruzi infection. Genomics 2008;91:423-432.
Nagajyothi F, Desruisseaux MS, Thiruvur N, Weiss LM, Braunstein VL, Albanese C, Teixeira MM, de Almeida CJ, Lisanti MP, Scherer PE, Tanowitz HB. Trypanosoma cruzi Infection of Cultured Adipocytes Results in an Inflammatory Phenotype. Obesity (Silver Spring) 2008;16:1992-1997.
Park SS, Bae I, Lee YJ. Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron. J Cell Biochem 2008;103:1989-1998.
Park S, Ramachandran S, Kwon SH, Cha SD, Bae I, Cho CH, Song DK. Up-regulation of ATP-sensitive potassium channels for estrogen-mediated cell proliferation in human uterine leiomyoma cells. Gynecologic Endocrinology 2008;24:250-256.
Ramachandran S, Kwon KY, Shin SJ, Kwon SH, Cha SD, Bae I, Cho CH. Cyclin-dependent kinase inhibitor p27Kip1 controls growth and cell cycle progression in human uterine leiomyoma. Korean J Medical Science 2008;23:667-673.
Seley-Radtke KL, Zhang Z, Wauchope OR, Zimmermann SC, Ivanov A, Korba BE. Hetero-expanded purine nucleosides. Design, synthesis and preliminary biological activity. Nucleic Acids Symp Ser (Oxf). 2008;52:635-636.
Tang Y, Kitisin K, Jogunoori W, Li C, Deng CX, Mueller SC, Ressom HW, Rashid A, He AR, Mendelson JS, Jessup JM, Shetty K, Zasloff M, Mishra B, Reddy EP, Johnson L, Mishra L. Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling. Proc Natl Acad Sci U S A 2008;105:2445-2450.
Thibodeaux CA, Liu X, Disbrow GL, Zhang Y, Rone JD, Haddad BR, Schlegel R. Immortalization and transformation of human mammary epithelial cells by a tumor-derived Myc mutant. Breast Cancer Res Treat July 20, 2008 [Epub ahead of print]
Tilli MT, Parrish AR, Cotaria I, Jones LP, Johnson MD, Furth PA. Comparison of mouse mammary gland imaging techniques and applications: reflectance confocal microscopy, GFP imaging, and ultrasound. BMC Cancer 2008;8:21.
Yun C, Mendelson J, Blake T, Mishra L, Mishra B. TGF-beta signaling in neuronal stem cells. Dis Markers 2008;24:251-255.
Zhang W, Chen Y, Swift M R, Tassi E, Stylianou DC, Gibby KA, Riegel AT, Wellstein A. Effect of FGF binding protein-3 on vascular permeability. J Biol Chem 2008;283:28329-37.
